Cell3iMager Estier is a versatile stage-top optical coherence tomography (OCT) instrument that allows non-invasive analysis of the 3D structures including spheroids, organoids, tubular structures and tissues etc.

3D Live -Cell Imaging using Infra red laser Tomography

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ESTIER imaging technology enables visualization of in vitro and ex vivo dynamics of the 3D structures (spheroids), angiogenic vessels (neovasculature, sprout formation), gut model, skin models conveniently, by quantitating and monitoring the morphological changes occurring during the culture.

Curious how our OCT technology works?

SCREEN has established itself as a leader in developing OCT system with stage-type implementation suitable for in vitro / ex vivo based preclinical research. 

Accelerate drug discovery, screening, profiling with high-content imaging

The infra read is able to penetrate through the spheroid as deep as 200 uM allowing the imaging of the core.

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Tumor spheroids

Vasculature formation formation

Ideal for growth monitoring and quantifying the neovasculature, sprout formations in angiogenesis research and tumor angiogenesis.

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Kidney-like structure 3D

Estier technology is highly amenable to examining various structures including tissues. The technology is able to image the kidney tubules in great detail.

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3D Spheroid formation

Time lapse measurement captures the spheroid formation cultured over a period of hours and days.

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Drug treatment enhances spheroid collapse

Many drugs do not induce the shrinkage of tumor spheroids, but enhance their efficacy by inducing loss of spheroid shape or cause the collapse of spheroids post drug treatment. These events can be captured in time lapse to pin point effect.

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