The MED64 has been used in the field of neuroscience for nearly two decades and is validated by hundreds of publications. The MED64’s lowest-impedance electrodes resolve even small signals from acute brain slices and provide high-quality evoked signals. Recording in an humidified incubator (where neurons are the healthiest) enables long-term recording.

Examples:

In vitro Micro-electrode array assay for evaluating in vivo-like convulsive activity in hiPSC-derived neuron and astrocyte co-culture

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Functional characterization of human induced pluripotent stem cell-derived sensory neurons using a high-sensitivity micro-electrode array

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Neurotoxicology screening using a high-sensitivity MEA platform

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Higher throughput micro-electrode array to investigate of role of NMDA receptor in synaptic plasticity in acute brain slices

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Studies for antiepileptic drug targets on acute brain slices using medium throughput MEA system

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Drug Effects On SCN Neurons

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Recording Of Single Unit Activities From Substantia Nigra

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Single unit activities from spinal cord slices

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Chronic Drug Effects On Cultured Rat Hippocampal Slices

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Longevity Of LTP In Cultured Hippocampal Slices

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Spontaneous Activities From Cultured Cerebellum

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Drug Effects On iPSC-derived Neurons

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Evaluation of anti-epilepsy drug effects on iPSC-derived neurons
Induction and suppression of epileptiform activities are examined using the MED64.

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Long‐term potentiation and depression phenomena in human induced pluripotent stem cell‐derived cortical neurons

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Recording From DRG Neurons

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Effects of capsaicin on DRG neuron firing
Rat DRG neurons are cultured on a MED Probe (4 days in culture) and changes of spontaneous firings with temperature variation and administration of Capsaicin is observed.

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MED64: Record important extracellular signals that can be hidden by other systems!

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