Imaging spheroids using conventional or even automated microscopes is a slow, low throughput process. High content imaging systems overcome some of these throughput issues, but are comparatively expensive, and still suffer from slow image capture/processing, and image analysis software not optimized for 3D spheroids. The Cell3iMager neo overcomes these limitations, featuring high-resolution scanning (up to 9600 dpi) without compromising scan time. This minimizes ‘out of incubator’ time to avoid jeopardizing cell health during analysis.
The powerful automated measurement and analysis software eliminates cumbersome manual morphological measurements and improves data reproducibility. Simply scan, measure, and analyze. Typical spheroid analysis includes a < 1 minute plate scan followed by a 20 to 30 second auto-measurement step. Data can be reviewed and processed in the software module, or exported for analysis in your preferred statistical software package. Rapid scan time (96-well plate in <1 minute) increases throughput (30 × 384-well plates/hour in the cc-5000 vs 2.5 plates/hour with conventional systems) Preset plate definitions for all major hanging drop, ULA, and micropatterned 3D cell culture platforms (6-, 12-, 24-, 48-, 96-, 384-well), dishes.